NWO SEM Sleep Society
LITERATURE WATCH

E. Cardiovascular Disorders and Sleep

J Clin Sleep Med 2005; 1(3): 271-276

Chest. 2005 Oct;128(4):2123-9.



Effects of Oxygen Therapy on LV function in patients with Cheyne Stokes
Respiration and CHF
J Clin Sleep Med 2005; 1(3): 271-276
10 patients with severe CHF (LVEF 12 +/- 5%) and
Cheyne Stokes Respiration, patients were given oxygen
therapy and re-evaluated  one month later.  
Nocturnal oxygen therapy decreases Apnea Hypopnea
Index in these patients but there is no improvement in LV
function.  Total sleep time, sleep efficiency, and sleep
architecture also remain unchanged

Continuous Positive Airway Pressure Treatment in Sleep Apnea Prevents New
Vascular Events After Ischemic Stroke
Chest. 2005 Oct;128(4):2123-9.
•        Demographic data, vascular risk factors, clinical
manifestations associated to sleep apnea-hypopnea
syndrome, and neurologic parameters were recorded in a
group of patients presenting with acute ischemic stroke at
least 2 months previously.
•        A polysomnographic study was carried out 2
months after the acute episode in all patients, with the
prescription of CPAP in the event of an apnea-hypopnea
index (AHI)  20.
•        Two groups were defined: patients who could
tolerate CPAP (group 1), and patients who could not
tolerate CPAP after 1 month of initial adaptation (group
2). They were followed for 18 months.
•        The incidence of new vascular events was greater
in group 2 (6.7%) vs group 1 (36.1%; long-rank, p = 0.03).
•        Intolerance of CPAP increased the probability of a
new vascular event fivefold (odds ratio, 5.09) adjusted for
other vascular risk factors and neurologic indexes.